Streamlining Macrophage Polarization Workflows | The Scientist

Macrophages are critical immune cells that modulate the body’s response to infection, injury, inflammation, disease, and healing. Researchers differentiate and polarize cryopreserved monocytes into macrophage subtypes, then use live-cell imaging to validate their function. However, the phenotype and phagocytic ability of resulting macrophages can differ depending on the protocols used.

Download this article to explore a handy guide to optimizing macrophage polarization and functional assays for high-throughput workflows related to immunotoxicity and drug discovery studies.