The Holy Grail Hunt in De Novo Antibody Design

The Holy Grail Hunt in De Novo Antibody Design

Monoclonal antibodies (mAbs) have become a prominent therapeutic modality due to their binding specificity and ability to engage a diverse range of targets. However, isolating mAbs remains a laborious process, traditionally requiring animal immunization or vast library screens of randomly generated variants. To address these limitations, a research team at the University of Washington, led…

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How to judge a book by its cover

How to judge a book by its cover

Prizes for book cover design are creating a space for visual and literary arts to meet /news/talking-point/book-cover-design-oxford-bookstore-book-cover-prize-publishing-next-industry-awards-111713670258266.html 111713670258266 story Art historian Alka Pande is multi-tasking. When talking about book cover design in the run-up to the Oxford Bookstore Book Cover Prize announcement anytime this month, she cuts out to handle something else for a minute….

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India calls Trump's tariff threat over Russian oil 'unjustified'

India calls Trump’s tariff threat over Russian oil ‘unjustified’

India has called Donald Trump’s threat of “substantially” higher tariffs over its purchase of oil from Russia “unjustified and unreasonable”. In a post on Truth Social, the US president warned he would raise levies, saying India “don’t care how many people in Ukraine are being killed by the Russian War Machine”. India is currently among…

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Producing Tumor-infiltrating Lymphocyte Therapeutics | The Scientist

Producing Tumor-infiltrating Lymphocyte Therapeutics | The Scientist

Tumor-infiltrating lymphocytes (TILs) are immune cells that naturally recognize and penetrate tumors to kill cancer cells, making them a promising approach for treating solid tumors. This potential was recently validated by the FDA’s accelerated approval of the first TIL therapy, lifileucel, for advanced melanoma. Developing and manufacturing TILs for the clinic requires a robust workflow…

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Building electronics that don’t die: Columbia's breakthrough at CERN

Building electronics that don’t die: Columbia’s breakthrough at CERN

The Large Hadron Collider (LHC) is tough on electronics. Situated inside a 17-mile-long tunnel that runs in a circle under the border between Switzerland and France, this massive scientific instrument accelerates particles close to the speed of light before smashing them together. The collisions yield tiny maelstroms of particles and energy that hint at answers…

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Trans non-binary runner Hiltz slams ‘slippery slope’ gene tests

Trans non-binary runner Hiltz slams ‘slippery slope’ gene tests

Transgender and non-binary US distance runner Nikki Hiltz criticized World Athletics’ plans to introduce gene testing for female athletes on Saturday, saying the move would be a “slippery slope.” Hiltz was assigned female at birth and came out as transgender and non-binary in 2021, and uses they/them pronouns. The US runner described the introduction of…

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It’s official! Sidharth Malhotra-Janhvi Kapoor starrer Param Sundari to release on August 29 : Bollywood News

It’s official! Sidharth Malhotra-Janhvi Kapoor starrer Param Sundari to release on August 29 : Bollywood News

Earlier this month, Bollywood hungama reported that the Sidharth Malhotra and Janhvi Kapoor starrer Param Sundari will hit the theatres either on August 29 or September 5. The makers, Maddock Films, have now revealed that the film will be releasing in theatres on August 29. It’s official! Sidharth Malhotra-Janhvi Kapoor starrer Param Sundari to release…

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