Researchers investigated collagen IV’s thermal instability, finding that a cystine knot keeps collagen threads together and helps facilitate refolding. Image credit:© Istock, quantic69 As the foundation for connective tissues like tendons, bones, cartilage, and skin, collagen is the most abundant protein in the human body. It serves as the body’s scaffolding, supporting cells as they…
In rainy season brings with it a refreshing change from the scorching summer heat, filling the environment with cool breezes, the earthy aroma of wet soil, and a sense of calm. However, this season also brings an increase in humidity and a higher risk of infections, indigestion, and respiratory issues. In such a scenario, paying…
A school bullying incident in southern China has sparked a series of protests and calls for more justice for the 14-year-old victim. A video of the girl being slapped, kicked and forced to kneel by three other minors went viral in the Jiangyou city in Sichuan province last week. The police said the three suspects…
Monoclonal antibodies (mAbs) have become a prominent therapeutic modality due to their binding specificity and ability to engage a diverse range of targets. However, isolating mAbs remains a laborious process, traditionally requiring animal immunization or vast library screens of randomly generated variants. To address these limitations, a research team at the University of Washington, led…
A team of UC Merced researchers has shown that tiny artificial cells can accurately keep time, mimicking the daily rhythms found in living organisms. Their findings shed light on how biological clocks stay on schedule despite the inherent molecular noise inside cells. The study, recently published in Nature Communicationswas led by bioengineering Professor Anand Bala…
Prizes for book cover design are creating a space for visual and literary arts to meet /news/talking-point/book-cover-design-oxford-bookstore-book-cover-prize-publishing-next-industry-awards-111713670258266.html 111713670258266 story Art historian Alka Pande is multi-tasking. When talking about book cover design in the run-up to the Oxford Bookstore Book Cover Prize announcement anytime this month, she cuts out to handle something else for a minute….
India has called Donald Trump’s threat of “substantially” higher tariffs over its purchase of oil from Russia “unjustified and unreasonable”. In a post on Truth Social, the US president warned he would raise levies, saying India “don’t care how many people in Ukraine are being killed by the Russian War Machine”. India is currently among…
Tumor-infiltrating lymphocytes (TILs) are immune cells that naturally recognize and penetrate tumors to kill cancer cells, making them a promising approach for treating solid tumors. This potential was recently validated by the FDA’s accelerated approval of the first TIL therapy, lifileucel, for advanced melanoma. Developing and manufacturing TILs for the clinic requires a robust workflow…
