A Selective Protein Regulates Chronic, But Not Acute, Inflammation

A Selective Protein Regulates Chronic, But Not Acute, Inflammation

Researchers at Massachusetts General Hospital identified a novel nuclear autophagy-based mechanism that distinguishes chronic inflammation from its acute counterpart. Image credit:© Istock, Dr_Microbe Anyone who’s ever scraped their knee on a dirty playground is familiar with the stinging inflammation that manifests soon after the injury. It’s the immune system’s effort to restrict and neutralize any…

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A Fungus, Not Its Insect Host, Paints the World Red

A Fungus, Not Its Insect Host, Paints the World Red

A fungus that lives in a symbiotic relationship with the lac insect produces a red-colored pigment used for dyeing textiles and handicrafts. Image credit:© Istock, AAGGraphics For thousands of years, artisans have been dyeing textiles, jewelry, and handicrafts with a rich, vibrant red pigment that they obtain from lac insects. The most widely-cultivated lac insect,…

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Why Does Acute Pain Get Better, But Chronic Pain Persist?

Why Does Acute Pain Get Better, But Chronic Pain Persist?

Researchers described a new braking mechanism in the brain that prevents normal pain from persisting for a long time, the collapse of which leads to chronic pain. Image credit:© Istock, Prostock-Studio In a laboratory at the Hebrew University of Jerusalem, Alexander Binshtoka pain neurobiologist, and his group peer into rodent brains to understand the mechanisms…

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Sustainable Practices Utilizing Genomics in New Zealand Wine Production

Sustainable Practices Utilizing Genomics in New Zealand Wine Production

New Zealand’s wine industry stands as a critical contributor to the nation’s economy and reputation on the global stage. However, climate variability, disease outbreaks, and growing environmental concerns have placed pressure on vineyards to adopt more sustainable practices. By embracing cutting-edge genomics, New Zealand wine producers are revolutionizing the way they approach crop breeding and…

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Non-Neuronal Cells Can “Remember” Certain Stimuli

Non-Neuronal Cells Can “Remember” Certain Stimuli

Researchers from New York University demonstrate memory-pathways driven learning effect in non-neuronal cells. Image credit:©iStock.com, Jian Fan In the early 1970s, neuropsychiatrist Eric Kandel and his colleagues at New York University found that even invertebrates can remember, in their studies on the gill and syphon withdrawal reflex response to painful stimuli in the sea slug,…

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FDA Announces Plan to Phase Out Animal Testing. Will That Work?

FDA Announces Plan to Phase Out Animal Testing. Will That Work?

With the FDA’s goal of replacing animal testing, scientists look to organoids and organ-on-a-chip technologies as replacement alternatives. Image credit:Wyss Institute at Harvard University In April of this year, the Food and Drug Administration (FDA) announced a new roadmap that aims to replace animal testing in the development of new drugs with more human-relevant methods….

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Accelerating Recombinase Reprogramming with Machine Learning

Accelerating Recombinase Reprogramming with Machine Learning

This webinar will be hosted live and available on-demand. Wednesday, September 24th, 202511:00 am – 12:00 PM The future of gene editing depends on tools that are programmable, scalable, and adaptable to diverse disease contexts. Recombinases are emerging as a promising solution, but optimizing their performance requires a robust blend of experimental and computational strategies….

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Regeneration Discovery May One Day Inform Hearing Loss Treatment

Regeneration Discovery May One Day Inform Hearing Loss Treatment

Hair cells in the inner ear detect mechanical stimuli from sound waves and convert them into electrical signals that the brain can interpret. Some animals, such as zebrafish, can regenerate their inner ear hair cells upon damage, but their mammalian counterparts are much more limited in this capacity. To understand why, developmental biologist Tatjana Piotrowski…

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