Technology

AAV Avenues for Cell and Gene Therapy

Law of Divine LifeAugust 15, 2025August 15, 202503 mins

LIVE Symposium

September 17-18, 2025
10:00 AM – 2:00 PM

Adeno-associated viruses (AAVs) have emerged as essential tools for delivering genetic material into tissues and engineering therapeutic cells. As gene and cell therapies advance, researchers optimize AAV design and enhance vector production to improve targeting, precision, and safety.

In this two-day symposium hosted by The Scientistexperts will discuss the latest advancements, practical applications, and ongoing challenges related to the use of AAVs in cell and gene therapy.

Topics to be covered

Investigating AAV serotype tropism in vivo using fluorescent reporter mouse models
Defining the minimal adenoviral helper gene set for improved AAV production and safety
Exploring AAV-based immunomodulation to prevent transplant rejection
Developing enhancer-driven AAV vectors for selective gene delivery to brain endothelial cells
Strategies for optimizing chemically defined media for scalable AAV production
Customizing viral vector design for cell-specific gene modulation and disease modeling in neurological research
Examining sex-specific differences in AAV immunogenicity

Bill Lagor, PhD
Kyle and Josephine Morrow Endowed Professor
Department of Integrative Physiology
Baylor College of Medicine

Nerea Zabaleta, PhD
Researcher
Centre for Applied Medical Research
University of Navarra

Matt Hirsch, PhD
Associate Professor
Department of Ophthalmology
University of North Carolina at Chapel Hill

Xiangmin Xu, PhD
Chancellor’s Professor, Department of Anatomy and Neurobiology
Director, Center for Neural Circuit Mapping
School of Medicine
University of California, Irvine

Hirotaka Kuroda, Phd
R&D Engineer
Shimadzu Corporation

Ajinkya Sase, Phd
Application Scientist
Vector Biolabs

Ronit mazor, phd
Principal Investigator and Laboratory Chief
Gene Transfer Immunogenicity Branch
Center for Biologics Evaluation and Research
US Food and Drug Administration